Sodium polyanethole sulfonate (SPS), with the chemical formula C₁₉H₂₅NO₅S and CAS number 55963-78-5, is a white to pale yellow crystal or powder. Due to its unique chemical properties and wide range of applications, SPS plays a vital role in various industries, including medicine, diagnostic reagents, and materials science. This article will provide a detailed introduction to the characteristics, main uses, and applications of SPS in various fields.

Basic Properties of SPS

SPS is a versatile chemical substance, presenting as white to pale yellow crystals or powder. Its chemical structure is stable and its properties are maintained under a wide range of environmental conditions, making it highly effective in a variety of applications. SPS’s chemical stability and biocompatibility make it particularly important in the biomedical field.

Main Applications

Medical Field

★ Blood Culture

SPS plays a vital role in blood cultures. It neutralizes trace amounts of antibiotics in the blood, thereby increasing the positive rate of blood culture results. This property makes SPS widely used in anaerobic or biphasic culture flasks, helping doctors more accurately diagnose the source of infection.

★ Anticoagulant

SPS exerts its anticoagulant effect by increasing the activity of antithrombin III, inhibiting the activity of serine proteases, thrombin, and activating factors essential for the coagulation process. This function is of great significance for the prevention and treatment of thrombotic diseases.

★ Promotes Pathogen Growth

SPS can neutralize lysozyme, inhibit phagocytosis, inactivate some aminoglycoside antibiotics, and inhibit the complement cascade, thereby promoting microbial growth. This property is very useful in pathogen culture and research, helping scientists better understand and control infectious diseases.

Other Applications

★ Diagnostic Reagent

SPS is used as a diagnostic reagent to inhibit blood coagulation in vitro. This application is very important in clinical diagnosis, helping doctors more accurately assess a patient’s coagulation status.

★ Preparation of Bifunctional/Polymer Composite Gel Beads

SPS has also been used in the preparation of bifunctional/polymer composite gel beads. This material has potential applications in drug delivery, tissue engineering, and other fields.

★ Colloidal Solution Stabilization

SPS has a stabilizing effect in colloidal solutions, such as milk and gelatin. This property also makes SPS useful in the food industry and cosmetics manufacturing.

Application Examples

1. Medical Application Examples

In the medical field, SPS applications include but are not limited to:

★ Blood Culture Optimization: The addition of SPS can significantly improve the positive rate of blood cultures, especially in the presence of antibiotic interference.

★ Anticoagulant Therapy: As an anticoagulant, SPS can be used to prevent and treat thrombotic disorders such as deep vein thrombosis and pulmonary embolism.

★ Pathogen Culture: SPS can promote the growth of pathogens, facilitating the rapid and accurate diagnosis of infectious diseases.

2. Industrial Application Examples

In the industrial field, SPS applications include but are not limited to:

★ Diagnostic Reagent Development: SPS can be used to develop new diagnostic reagents, improving diagnostic accuracy and efficiency.

★ Materials Science: SPS’s role in the preparation of bifunctional/polymer composite gel beads can be used in drug delivery systems to improve drug targeting and bioavailability.

★Food Industry: SPS’s stabilizing effect in colloidal solutions can be used to improve the texture and stability of foods, such as in dairy and gelatin products.

Conclusion

Sodium polyanethole sulfonate (SPS) is a chemical with diverse uses and properties. In medicine, it plays an important role as a blood culture additive, anticoagulant, and pathogen growth enhancer. SPS also demonstrates its unique value in other fields, such as diagnostic reagents, materials science, and the food industry. With the deepening of scientific research and technological advancements, the application areas of SPS will continue to expand, making greater contributions to improving human health and quality of life.

This article provides a comprehensive introduction to the properties, uses, and applications of sodium polyanethole sulfonate (SPS), hoping to provide you with valuable information. If you have further interest or need to learn more about SPS, please contact us.