Basic Information

English Name: L-Selenomethionine

CAS Number: 3211-76-5

Molecular Formula: C₅H₁₁NO₂Se

Molecular Weight: 196.11
Selenium Content: 40% 0.5%

Other Names:

L-(+)-Selenomethionine

(S)-(+)-2-Amino-4-(methylseleno)butyric Acid

Selenomethionine

L-Selenomethionine

L-Selenomethionine

Seleno-L-Methionine

L(+)-Selenomethionine

Seleno-L-Methionine

L-Selenomethionine Standard

L-(+)-Selenomethionine

Selenomethionine (L-Selenomethionine) Assay Standard

Physical and Chemical Properties

Appearance: White to off-white powder

Color: White to off-white

Melting point: 265°C

Specific rotation: +18° (c=1, 1N HCl)

Boiling point: 320.8±37.0°C

Refractive index: 18° (c=0.5, 2 mol/L HCl)

Applications

Biological activity:

Exhibits antioxidant activity and increases glutathione peroxidase activity in endothelial cells.

Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations, and interference with protein tyrosine signaling.

Exhibits dose-dependent growth inhibition against cancer cell lines (such as MCF-7/S breast cancer, DU-145 prostate cancer cells, and UAC-375 melanoma cells), while growth inhibition of normal fibroblasts requires 1 mM selenomethionine.

Protein structure analysis:

Can be used for protein structure analysis. By feeding bacteria with this product, selenium is substituted at specific positions in the resulting proteins, facilitating structural determination.

Food and Health Products:

In the United States, Japan, and Europe, it is primarily used in food, health products, and pharmaceuticals.

In China, it can be used in health foods and is listed as selenomethionine in health product ingredient catalogs.

Selenomethionine is an important organic selenium compound with numerous health benefits, including antioxidant, anti-cancer, and immune-enhancing properties. It is widely used in food, health products, and scientific research.