Basic Information

English Name: Phenazine Methosulfate

CAS Number: 299-11-6

Molecular Formula: C₁₄H₁₄N₂O₄S

Molecular Weight: 306.34

Other Names:

5-Methylphenazine methylsulfate, methylthiophenazine, methylthiophenazine, phenazine methylsulfate, N-methylphenazine methylsulfate, 5-methylphenazine methylsulfate, phenazine methylsulfate (PMS), 5-methylphenazine monomethylsulfate, phenazine dimethylsulfate (+4°C), N-methyldibenzopyrazine methylsulfate

Physicochemical Properties

Appearance: Dark yellow to brown crystalline powder

Melting Point: 158-160°C

Solubility: 0.2 g/mL in water (20°C); solution is dark orange.

Density: 1.3395 g/cm³

Refractive Index: 1.6930

Sensitivity: Light-sensitive

Stability: Stable, but incompatible with strong oxidants

Applications

Biochemical Research: Phenazine methoxymethyl ester is a commonly used electron transporter, often used in NADH/NAD⁺ oxidoreductase assays.

Pharmaceutical Intermediate: Used in the synthesis of certain drugs, such as a component of succinate dehydrogenase substrate solution.

Research Uses:

Induces superoxide radical production in erythrocyte suspensions to study their effects on erythrocyte deformability.

Used as a component of Complex II histochemistry culture medium.

Storage Conditions

Temperature: Recommended storage at -20°C.

Environment: Protect from light, sealed.

Phenazine methoxymethyl ester is an important biochemical reagent widely used in biochemical research and the synthesis of pharmaceutical intermediates. It has excellent electron transport properties and is often used in NADH/NAD⁺ oxidoreductase assays.