Basic Information

Chemical Name: 2-Iodo-5-Methylbenzoic Acid

English Name: 2-Iodo-5-Methylbenzoic Acid

CAS Number: 52548-14-8

Molecular Formula: C₈H₇IO₂

Molecular Weight: 262.04

Appearance: White to pale yellow crystals or powder

Melting Point: 122-124°C

Boiling Point: 321.4 ± 30.0°C (estimated)

Density: 1.867 ± 0.06 g/cm³ (estimated)

Acidity (pKa): 2.93 ± 0.10 (estimated)

Storage Conditions: 2-8°C (protect from light)

Chemical Properties

Form: Solid

Solubility: Poor solubility in water

Stability: Stable at room temperature, but may decompose under light and high temperatures.

Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydroiodic acid

Applications

Organic Synthesis: 2-Iodo-5-methylbenzoic acid is an important intermediate in the synthesis of various organic compounds and is widely used in organic synthesis reactions.

Drug Synthesis: This compound is an important intermediate in the synthesis of certain drugs, such as suvorexant.

Research Uses: In biochemistry and drug discovery, 2-Iodo-5-methylbenzoic acid is used for synthesis and structural studies.

2-Iodo-5-methylbenzoic acid is an important organic synthesis intermediate widely used in organic synthesis, drug synthesis, and biochemistry research. It has particularly promising applications in drug synthesis, for example, as an intermediate in the synthesis of drugs such as suvorexant. However, caution should be exercised regarding its potential for skin and eye irritation, and appropriate safety precautions should be taken when handling it.