Informations de base

Chemical Name: Ethyl N-(tert-Butoxycarbonyl)-D-pyroglutamate

CAS Number: 144978-35-8

Molecular Formula: C₁₂H₁₉NO₅

Molecular Weight: 257.29

Appearance: White to pale yellow crystals or powder

Melting Point: 54.0-58.0°C

Applications

Organic Synthesis: Ethyl BOC-D-pyroglutamate is primarily used as a functional group protecting agent in organic synthesis reactions, protecting the hydroxyl group of the pyroacid, thereby preventing it from participating in unwanted reactions.

Biomedicine: Ethyl BOC-D-pyroglutamate has potential applications in the biopharmaceutical field. It has been found to alleviate the symptoms of cardiovascular diseases, including hypertension and heart disease. It also possesses anti-inflammatory and antioxidant properties, showing potential in the treatment of inflammatory diseases and oxidative stress-related diseases.

Natural Product Synthesis: Ethyl BOC-D-pyroglutamate has a wide range of applications in natural product synthesis. It can be used as a catalyst to selectively modify chiral centers, yielding target compounds.

Drug Discovery: Ethyl BOC-D-pyroglutamate can be used as a catalyst in synthetic processes, improving efficiency and yield. It can also be used to introduce protecting groups into drug molecules, protecting sensitive functional groups and enhancing compound stability.

Ethyl BOC-D-pyroglutamate (Ethyl N-(tert-Butoxycarbonyl)-D-pyroglutamate) is an important organic synthesis intermediate widely used in organic synthesis, biopharmaceuticals, natural product synthesis, and drug discovery. Its application prospects in biopharmaceuticals are particularly promising, with potential anti-inflammatory, antioxidant, and cardiovascular protective effects. However, caution should be exercised regarding its potential for skin and eye irritation, and appropriate safety precautions should be taken when using it.